The study of the relationship between genes and response to drugs has been the subject of intensive research over the past two decades and robust evidence now exists to support testing under clinical conditions.
There is a great deal of variability in how a patient responds to medications due to the genes that govern drug metabolism, and this can therefore impact drug efficacy. Pharmacogenomics empowers the doctor to provide specific medical interventions, based on the patient’s genetic profile, and replaces the current trial and error approach to drug therapy.
A pharmacogenomics test gives insight into how each patient metabolizes, transports, and binds specific prescription drugs, which in turn allows physicians to prescribe those compounds that are most likely to prove efficacious, to avoid those that will not, and in many instances to adjust doses to safe yet therapeutic levels. Such a personalized approach to medicine has the power to produce better results, particularly for individuals whose genetic profile puts them at risk of experiencing either treatment failure or an adverse reaction from a given drug.